Stem Cell Transplant Restores Memory, Learning in Mice

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A study at the University of Wisconsin-Madison has proved that human embryonic stem cells can heal neurological damage when implanted into the brains of mice. After implantation, these stem cells become two common types of neurons associated with memory, emotions, and learning.

The researchers used mice that accept trans-species transplants and whose brains suffered damage to the medial spectrum, which is associated with learning and memory. The researchers also chemically biased the implanted stem cells to develop into neural cells. The mice achieved higher scores for tests associated with learning and memory post-transplant than they achieved prior the procedure.

The results of the study may be applied to the production of drug screening models.

Liu Y, Weick J P, et al. Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits. Nature Biotechnology. (April 2013).