Chinese Medicine to Treat Traumatic Brain Injury
Posted By The Scarlett Law Group
One of the most serious effects of a traumatic brain injury is the secondary
injury caused by inflammation in the brain. Many clinical trials have
been initiated in the last several years to find a drug therapy that will
effectively reduce this inflammation. Unfortunately, to date, no therapy
has succeeded in these clinical trials.
The inflammation response in the secondary brain injury is a complex cascade
of changes in neurotransmitters and cellular response. The challenge of
a successful drug therapy is targeting the neural pathway that most effectively
inhibits inflammation. In traditional Chinese medicine, treatments tend
to target more than one biological process at a time, and may, therefore,
have the potential to be effective in altering those neural pathways.
First described in text 185 years ago, the Chinese medicine Xuefu Zhuyu
was originally derived from 11 herbs as a treatment for inflammation.
Recently, the prescription of Xuefu Zhuyu (XFZY) was tested in an animal
study for its effect on traumatic brain injury. XFZY significantly enhanced
cognition (via spatial memory tests) and also significantly reduced the
proteins in the brain that lead to inflammation. The benefit of XFZY is
dose-dependent, and clinical studies will have to show success in human
trials for it to pass as an effective treatment for TBI. In the meantime,
it may be a promising alternative where other drug studies have failed.